Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9736841 | 0.99 | ATM (0.56) | HTR1ADRD2KCNH2ATMMEN1 | |
| SCHEMBL9736715 | 0.92 | ATM (0.54) | HTR1ADRD2KCNH2ATMMEN1 | |
| SCHEMBL9737244 | 0.89 | DRD2 (0.54) | HTR1ADRD2ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9735824 | 0.88 | DRD2 (0.55) | HTR1ADRD2ATMMEN1KMT2A | |
| SCHEMBL9739717 | 0.88 | ATM (0.62) | HTR1ADRD2KCNH2ATMMEN1 | |
| Hydrochloric Acid SCHEMBL9736847 | 0.87 | ATM (0.64) | HTR1ADRD2KCNH2ATMMEN1 | |
| Hydrochloric Acid SCHEMBL9736860 | 0.87 | ATM (0.64) | HTR1ADRD2KCNH2ATMMEN1 | |
| SCHEMBL9738397 | 0.85 | ABCB1 (0.54) | HTR1ADRD2ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9736942 | 0.84 | ATM (0.53) | HTR1ADRD2ATMMEN1KMT2A | |
| SCHEMBL9737269 | 0.82 | HTR2A (0.64) | HTR1ADRD2ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110816-A | Urogenital disorders | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) (FR) | 1992-05-05 | — | — | US | disclosed |