Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28270211 | 0.96 | EPHX2 (0.61) | MEN1KMT2AEPHX2POLBFAAH | |
| SCHEMBL22271589 | 0.94 | EPHX2 (0.63) | MEN1KMT2AEPHX2FAAHHPGD | |
| SCHEMBL2431411 | 0.92 | EPHX2 (0.60) | MEN1KMT2AEPHX2FAAHHPGD | |
| SCHEMBL9196679 | 0.89 | EPHX2 (0.50) | MEN1KMT2AEPHX2POLBFAAH | |
| SCHEMBL29523215 | 0.86 | LMNA (0.56) | MEN1KMT2AHPGDALDH1A1CNR1 | |
| SCHEMBL25365126 | 0.86 | HDAC1 (0.55) | MEN1KMT2AHPGDL3MBTL1TSHR | |
| SCHEMBL13296294 | 0.85 | KMT2A (0.56) | MEN1KMT2AHPGDGAAALDH1A1 | |
| SCHEMBL23491692 | 0.85 | MEN1 (0.49) | MEN1KMT2AHPGDGAAALDH1A1 | |
| SCHEMBL22996060 | 0.84 | MEN1 (0.51) | MEN1KMT2AEPHX2FAAHGAA | |
| SCHEMBL9391884 | 0.84 | MEN1 (0.55) | MEN1KMT2AHPGDALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489070-A1 | NOVEL INHIBITORS OF THROMBIN. | BIOGEN INC (US) | 1992-06-10 | — | — | EP | disclosed |