SCHEMBL9736780

SCHEMBL9736780

Cc1cccc(OC(=O)CCCCC(=O)Oc2cccc(C)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.65
KMT2A Q03164 2/20 0.58
GAA P10253 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.50
MAPT P10636 2/20 0.49
ACHE P22303 1/20 0.48
ALOX5 P09917 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7980728 0.96 LMNA (0.65) LMNAKMT2AGAASMN1; SMN2MAPT
SCHEMBL8430064 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2
SCHEMBL30125136 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2
SCHEMBL27432548 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2
SCHEMBL30680466 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2
SCHEMBL8847008 0.92 LMNA (0.56) LMNAKMT2AGAASMN1; SMN2MAPT
SCHEMBL28008331 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2
SCHEMBL8846918 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2
SCHEMBL14360136 0.92 LMNA (0.56) LMNAKMT2AGAASMN1; SMN2
SCHEMBL28008648 0.92 KMT2A (0.57) LMNAKMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245836-B1 THERMOSENSITIVE RECORDING SHEET DAINIPPON INK AND CHEMICALS, INC. (JP) 1992-07-22 EP disclosed
US-4764500-A Thermosensitive recording sheet DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-08-16 US disclosed
EP-0245836-A2 Thermosensitive recording sheet DAINIPPON INK AND CHEMICALS, INC. (JP) 1987-11-19 EP disclosed