Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14036445 | 0.84 | HDAC1 (0.56) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL13959073 | 0.83 | NCF1 (0.50) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL7835368 | 0.81 | NCF1 (0.59) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL3820644 | 0.81 | HDAC1 (0.56) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL4849365 | 0.80 | NCF1 (0.57) | NQO1NCF1HDAC1HDAC2PDE10A | |
| Ammonia Solution, Strong SCHEMBL28426316 | 0.80 | NCF1 (0.57) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL7808259 | 0.80 | NCF1 (0.57) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL203756 | 0.80 | NCF1 (0.57) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL28254830 | 0.80 | NCF1 (0.62) | NQO1NCF1HDAC1HDAC2PDE10A | |
| SCHEMBL14125319 | 0.80 | HDAC1 (0.47) | NQO1NCF1HDAC1HDAC2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084463-A | Cardiovascular disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |