Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8962074 | 1.00 | PTGS2 (0.56) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8961965 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8961976 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8961997 | 0.83 | PTGS2 (0.64) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8962058 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8962054 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8962056 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8961993 | 0.81 | PTGS2 (0.60) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8962142 | 0.81 | PTGS2 (0.60) | PTGS2PTGS1ALOX5EEF2KSRC | |
| SCHEMBL8962140 | 0.81 | PTGS2 (0.60) | PTGS2PTGS1ALOX5EEF2KSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143928-A | Inhibitors of cyclooxygenase and lipoxygenase | WARNER-LAMBERT COMPANY (US) | 1992-09-01 | — | — | US | claimed |