Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571761 | 0.88 | MEN1 (0.63) | MEN1KMT2ACDC25BBCL2MCL1 | |
| SCHEMBL24730390 | 0.84 | PTPRC (0.59) | MEN1KMT2ACDC25BBCL2MCL1 | |
| SCHEMBL652915 | 0.81 | MEN1 (0.60) | MEN1KMT2ACDC25BBCL2MCL1 | |
| SCHEMBL1304448 | 0.81 | PTPRC (0.62) | MEN1KMT2ACDC25BBCL2MCL1 | |
| SCHEMBL29867916 | 0.80 | MEN1 (0.67) | MEN1KMT2ACDC25BBCL2MCL1 | |
| SCHEMBL30327427 | 0.80 | MEN1 (0.67) | MEN1KMT2ACDC25BBCL2MCL1 | |
| SCHEMBL236156 | 0.80 | MEN1 (0.67) | MEN1KMT2ACDC25BBCL2MCL1 | |
| Hydrochloric Acid SCHEMBL10785532 | 0.78 | MEN1 (0.63) | MEN1KMT2ACDC25BBCL2MCL1 | |
| Hydrochloric Acid SCHEMBL10789329 | 0.78 | MEN1 (0.63) | MEN1KMT2ACDC25BBCL2MCL1 | |
| Anthraquinone SCHEMBL28260408 | 0.77 | MEN1 (0.92) | MEN1KMT2ACDC25BBCL2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344110-B1 | SUBSTITUTED NAPHTHACENES-5,12-DIONES AND THEIR USE | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-5001243-A | Substituted naphthacene-5, 12-diones | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |