Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 12/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383849 | 1.00 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9383858 | 1.00 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9736966 | 1.00 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9383855 | 1.00 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9378233 | 0.83 | HMGCR (0.64) | HMGCR | |
| SCHEMBL10398500 | 0.83 | HMGCR (0.77) | HMGCR | |
| SCHEMBL9734648 | 0.80 | DPP4 (0.42) | HMGCR | |
| SCHEMBL9387195 | 0.80 | DPP4 (0.42) | HMGCR | |
| SCHEMBL9871180 | 0.79 | HMGCR (0.69) | HMGCR | |
| SCHEMBL9870588 | 0.78 | HMGCR (0.69) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145959-A | Enzyme inhibitors; antilipemic agents; treatment of atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5075311-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |