Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387195 | 1.00 | DPP4 (0.42) | DPP4GCGRHTTNCOA3MAPK1 | |
| SCHEMBL9735873 | 0.84 | DPP4 (0.41) | DPP4HTTNCOA3HMGCRMAPK14 | |
| SCHEMBL9735875 | 0.84 | DPP4 (0.41) | DPP4HTTNCOA3HMGCRMAPK14 | |
| SCHEMBL9384186 | 0.83 | GCGR (0.38) | GCGRMAPK1HMGCRESR1CHRM1 | |
| SCHEMBL9735137 | 0.83 | GCGR (0.38) | GCGRMAPK1HMGCRESR1CHRM1 | |
| SCHEMBL9736971 | 0.80 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9383849 | 0.80 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9383855 | 0.80 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9736966 | 0.80 | HMGCR (0.60) | HMGCR | |
| SCHEMBL9383858 | 0.80 | HMGCR (0.60) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145959-A | Enzyme inhibitors; antilipemic agents; treatment of atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| US-5075311-A | Anticholesterol agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |