SCHEMBL9737112

SCHEMBL9737112

Cc1cccc(CNCc2cccc(C)c2)c1

nearest known ligand 0.84

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.54
IDO1 P14902 2/20 0.52
ALDH1A1 P00352 2/20 0.51
CYP2D6 P10635 2/20 0.51
ACHE P22303 2/20 0.50
DNM1 Q05193 1/20 0.49
MMP13 P45452 1/20 0.49
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CXCR4 P61073 3/20 0.47
BACE1 P56817 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 1/20 0.45
HRH3 Q9Y5N1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15705379 0.92 CHRM2 (0.50) TAAR1IDO1ALDH1A1CYP2D6DNM1
SCHEMBL4911510 0.91 MEN1 (0.54) TAAR1IDO1ALDH1A1CYP2D6ACHE
SCHEMBL5034657 0.89 MEN1 (0.52) TAAR1IDO1ALDH1A1CYP2D6DNM1
SCHEMBL5352263 0.89 TAAR1 (0.48) TAAR1IDO1ALDH1A1CYP2D6ACHE
SCHEMBL4917404 0.89 MEN1 (0.52) TAAR1IDO1ALDH1A1CYP2D6DNM1
SCHEMBL4916688 0.89 MEN1 (0.52) TAAR1IDO1ALDH1A1CYP2D6DNM1
SCHEMBL14492306 0.88 CHRM2 (0.61) TAAR1CYP2D6CXCR4CYP1A2CYP3A4
SCHEMBL20724025 0.88 TAAR1 (0.48) TAAR1IDO1ALDH1A1CYP2D6ACHE
SCHEMBL27451191 0.87 TAAR1 (0.47) TAAR1IDO1ALDH1A1CYP2D6ACHE
SCHEMBL14492274 0.87 LMNA (0.56) ALDH1A1CYP2D6KDM4EHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2993198-B1 XYLYLENEDIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN MITSUBISHI GAS CHEMICAL CO (JP) 2017-09-27 EP disclosed
US-9562144-B2 Xylylenediamine composition, and method for producing polyamide resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2017-02-07 US disclosed
EP-2993198-A1 XYLYLENEDIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN Mitsubishi Gas Chemical Company, Inc. (JP) 2016-03-09 EP disclosed
US-20160039993-A1 XYLYLENEDIAMINE COMPOSITION, AND METHOD FOR PRODUCING POLYAMIDE RESIN MITSUBISHI GAS CHEMICAL COMPANY, INC (JP) 2016-02-11 US disclosed
US-5098810-A A hydrazone derivative charge transport compound and a pyrrolopyrrole charge generating compound material on a conductive substrate JAPAT LTD. (CH) 1992-03-24 US disclosed
EP-0089055-B1 DEAZAPURINE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 1987-06-03 EP disclosed
US-4571423-A Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-ones TAKEDA CHEMICAL INDUSTRIES LTD. (JP) 1986-02-18 US disclosed
EP-0089055-A2 Deazapurine derivatives Takeda Chemical Industries, Ltd. (JP) 1983-09-21 EP disclosed