SCHEMBL9737135

SCHEMBL9737135

CCOCC1(COCC)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 14/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737518 0.87 SOAT1 (1.00) SOAT1
SCHEMBL9737581 0.85 SOAT1 (0.83) SOAT1
SCHEMBL9742035 0.83 SOAT1 (0.59) SOAT1
SCHEMBL9740997 0.83 SOAT1 (0.59) SOAT1
SCHEMBL9738395 0.83 SOAT1 (0.86) SOAT1
SCHEMBL9740337 0.82 SOAT1 (0.77) SOAT1
SCHEMBL9737115 0.81 SOAT1 (0.72) SOAT1
SCHEMBL9737710 0.81 SOAT1 (0.72) SOAT1
SCHEMBL7075191 0.80 SOAT1 (1.00) SOAT1
SCHEMBL9699233 0.80 SOAT1 (0.75) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102900-A Antilipemic and anticholesterol agents RHONE-POULENC RORER S.A. (FR) 1992-04-07 US claimed
US-5102900-A Antilipemic and anticholesterol agents RHONE-POULENC RORER S.A. (FR) 1992-04-07 US disclosed
EP-0424195-A1 Imidazoles RHONE-POULENC SANTE (FR) 1991-04-24 EP disclosed