Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.63 |
| ▸ | CSNK1E | P49674 | 5/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17002242 | 0.78 | MAPK14 (1.00) | MAPK14CSNK1ECSNK1D | |
| SCHEMBL9737184 | 0.77 | MAPK13 (0.51) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL9737022 | 0.76 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL18857842 | 0.75 | MAPK14 (0.47) | MAPK14CSNK1ECSNK1D | |
| SCHEMBL739928 | 0.75 | MAPK13 (0.72) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL17002309 | 0.74 | MAPK14 (1.00) | MAPK14CSNK1ECSNK1DMAPK13MAPK12 | |
| SCHEMBL9736772 | 0.73 | MAPK13 (0.50) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL104130 | 0.73 | MAPK13 (0.82) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| Benzene SCHEMBL28852698 | 0.73 | MAPK13 (0.82) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL17002243 | 0.73 | MAPK14 (1.00) | MAPK14CSNK1ECSNK1DMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005148-A1 | IMIDAZOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS | RHONE-POULENC RORER LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |