Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572613 | 0.71 | HPGD (0.35) | ALDH1A1HPGDSMN1; SMN2TDP1POLB | |
| SCHEMBL9737711 | 0.70 | KMT2A (0.36) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9647723 | 0.70 | — | — | |
| SCHEMBL28675095 | 0.69 | HPGD (0.49) | ALDH1A1HPGDHTTKMT2APOLB | |
| SCHEMBL4572620 | 0.68 | MAPT (0.37) | ALDH1A1NPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL266573 | 0.66 | KMT2A (0.47) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8588321 | 0.64 | MEN1 (0.33) | ALDH1A1NPC1RAB9AKMT2APOLB | |
| SCHEMBL11724634 | 0.64 | GSK3B (0.39) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL19677094 | 0.62 | — | — | |
| SCHEMBL28382084 | 0.62 | CYP3A4 (0.37) | ALDH1A1TDP1HTTKMT2AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145703-A | Adding to foods to enhance flavor | HAARMANN & REIMER (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0459198-A2 | Thioalkanones, procedure for their preparation and their use | HAARMANN & REIMER GMBH (DE) | 1991-12-04 | — | — | EP | disclosed |