Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588511 | 0.68 | FDPS (0.51) | GSK3BALOX5GAANPC1RAB9A | |
| SCHEMBL21445082 | 0.65 | GSK3B (0.40) | GSK3BALOX5GAANPC1RAB9A | |
| SCHEMBL9350805 | 0.65 | CYP1A2 (0.44) | GSK3BGAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11433211 | 0.64 | ALOX5 (0.50) | GSK3BALOX5ALDH1A1KMT2APOLB | |
| SCHEMBL9737844 | 0.64 | ALDH1A1 (0.33) | GSK3BNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6536809 | 0.62 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8588740 | 0.62 | NPC1 (0.39) | GSK3BALOX5GAANPC1RAB9A | |
| SCHEMBL9639925 | 0.62 | ALOX5 (0.51) | GSK3BALOX5GAANPC1RAB9A | |
| SCHEMBL11605025 | 0.62 | MAP2K7 (0.43) | GSK3BGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27347277 | 0.61 | ALOX5 (0.47) | GSK3BALOX5GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053480-A | 1-THIADIAZOLYL-5-PHENOXY- AND PHENYLTHIOALKANOYLOXY IMIDAZOLIDINONES | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |