SCHEMBL9737876

SCHEMBL9737876

CCCON1C(C)(C)CC(OC(=O)CCCCC(=O)OC2CC(C)(C)N(OCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 2/20 0.45
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
EPHX2 P34913 5/20 0.37
TSHR P16473 2/20 0.35
DGKA P23743 1/20 0.34
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15389424 0.99 NAAA (0.48) NAAAKMT2AMEN1GAASMN1; SMN2
SCHEMBL10430890 0.96 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2
SCHEMBL6723839 0.94 NAAA (0.37) NAAAKMT2AMEN1GAASMN1; SMN2
SCHEMBL15388817 0.92 NAAA (0.50) NAAAKMT2AMEN1GAASMN1; SMN2
SCHEMBL3951982 0.90 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2
SCHEMBL12201034 0.90 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2
SCHEMBL13435126 0.90 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2
SCHEMBL15389142 0.90 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2
SCHEMBL14707369 0.90 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2
SCHEMBL5153897 0.90 NAAA (0.52) NAAAKMT2AMEN1GAAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed