Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.52 |
| ▸ | HTT | P42858 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL636220 | 0.89 | POLB (0.52) | SMN1; SMN2ALDH1A1LMNATP53TSHR | |
| SCHEMBL9352993 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL88416 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL2793675 | 0.82 | ALDH1A1 (0.65) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL3744646 | 0.82 | ALDH1A1 (0.65) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL11786266 | 0.80 | POLB (0.50) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL4296258 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL5606838 | 0.77 | TSHR (0.59) | SMN1; SMN2HTTALDH1A1TP53TSHR | |
| SCHEMBL15822354 | 0.76 | ALDH1A1 (0.53) | SMN1; SMN2HTTALDH1A1LMNATP53 | |
| SCHEMBL28190734 | 0.76 | BCHE (0.50) | HTTTSHRMMP2POLBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145926-A | Poly(indane ethers) | ALLIED-SIGNAL INC. (US) | 1992-09-08 | — | — | US | disclosed |