Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 12/20 | 1.00 |
| ▸ | BCL2 | P10415 | 11/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gossypol SCHEMBL30260519 | 1.00 | MCL1 (1.00) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL29798874 | 1.00 | MCL1 (1.00) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL3939 | 1.00 | MCL1 (1.00) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL29355719 | 1.00 | MCL1 (1.00) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL23014699 | 0.98 | MCL1 (0.97) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL27542391 | 0.98 | MCL1 (0.97) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL27755741 | 0.98 | MCL1 (0.97) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL28855396 | 0.98 | MCL1 (0.97) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL28166062 | 0.98 | MCL1 (0.97) | MCL1BCL2AKR1B1KDM4EMEN1 | |
| Gossypol SCHEMBL11156705 | 0.97 | MCL1 (0.94) | MCL1BCL2AKR1B1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112637-A | Using aqueous solution of tribasic acid | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1992-05-12 | — | — | US | disclosed |