Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257455 | 0.80 | MAPK1 (0.68) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7019511 | 0.79 | HSD17B10 (0.58) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| Carboxin SCHEMBL18392 | 0.78 | MAPK1 (1.00) | HSD17B10MAPK1RAB9ANPC1KMT2A | |
| Carboxin SCHEMBL8819780 | 0.78 | MAPK1 (1.00) | HSD17B10MAPK1RAB9ANPC1KMT2A | |
| SCHEMBL21874 | 0.76 | MAPK1 (0.56) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11247570 | 0.75 | HSD17B10 (0.55) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| Oxycarboxin SCHEMBL18897 | 0.74 | RAB9A (0.56) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8803600 | 0.74 | HSD17B10 (0.53) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| Oxycarboxin SCHEMBL28267507 | 0.74 | RAB9A (0.56) | HSD17B10MAPK1RAB9ANPC1SMN1; SMN2 | |
| Carboxin SCHEMBL20746329 | 0.74 | MAPK1 (0.90) | HSD17B10MAPK1RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5131940-A | 5,6-Dihydro-3-methyl-N-phenyl-1,4-dioxin-2-carboxamides | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-5070211-A | WHEAT AND BARLEY CROPS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1991-12-03 | — | — | US | disclosed |