Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738044 | 0.94 | AGTR1 (0.38) | AGTR1SLC33A1 | |
| SCHEMBL9740212 | 0.90 | AGTR1 (0.35) | AGTR1SLC33A1 | |
| SCHEMBL9739279 | 0.89 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9739916 | 0.89 | AGTR1 (0.34) | AGTR1SLC33A1 | |
| SCHEMBL9738171 | 0.88 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9739015 | 0.88 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9738485 | 0.85 | SLC33A1 (0.33) | AGTR1SLC33A1 | |
| SCHEMBL9739129 | 0.85 | AGTR1 (0.35) | AGTR1 | |
| SCHEMBL9739317 | 0.84 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9738118 | 0.83 | AGTR1 (0.37) | AGTR1SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | claimed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |