Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | CYBB | P04839 | 2/20 | 0.32 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28873682 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2HTR2BHTR1AHTR7TMEM97 | |
| SCHEMBL29946544 | 0.82 | NSD2 (0.36) | HTR2BHTR1AHTR7TMEM97SIGMAR1 | |
| SCHEMBL18119745 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ASOAT1MEN1 | |
| SCHEMBL334829 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2HTR2BHTR1AHTR7TMEM97 | |
| SCHEMBL5839553 | 0.73 | ALDH1A1 (0.33) | HTR2BHTR2C | |
| SCHEMBL31753138 | 0.72 | SMN1; SMN2 (0.35) | SMN1; SMN2HTR2BHTR1AHTR7TMEM97 | |
| SCHEMBL15890435 | 0.71 | SMN1; SMN2 (0.52) | SMN1; SMN2HTR2BHTR1AHTR7TMEM97 | |
| SCHEMBL13898705 | 0.69 | HTR2C (0.48) | HTR2BHTR1AHTR7TMEM97SIGMAR1 | |
| SCHEMBL4263866 | 0.68 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9ASOAT1MEN1 | |
| SCHEMBL3105747 | 0.68 | KDM1A (0.43) | SMN1; SMN2HTR2BNPC1RAB9ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089635-A | Antiprogesterone, antiglucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |