SCHEMBL9738284

SCHEMBL9738284

O=C(COP(=O)(O)O)[C@H](O)[C@@H](O)CO

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.46
TPI1 P60174 2/20 0.41
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
MPI P34949 1/20 0.37
PDE4A P27815 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440746 1.00 PGD (0.46) PGDTPI1PGK1PGK2MPI
SCHEMBL20608201 1.00 PGD (0.46) PGDTPI1PGK1PGK2MPI
SCHEMBL707542 1.00 PGD (0.46) PGDTPI1PGK1PGK2MPI
SCHEMBL22163754 0.91 PGD (0.40) PGDTPI1PGK1PGK2MPI
SCHEMBL22163755 0.91 PGD (0.40) PGDTPI1PGK1PGK2MPI
SCHEMBL19512307 0.89 PGD (0.43) PGDTPI1PGK1PGK2MPI
SCHEMBL9737043 0.89 PGD (0.43) PGDTPI1PGK1PGK2MPI
SCHEMBL16322088 0.89 PGD (0.43) PGDTPI1PGK1PGK2MPI
SCHEMBL851610 0.89 PGD (0.43) PGDTPI1PGK1PGK2MPI
SCHEMBL24438 0.89 PGD (0.43) PGDTPI1PGK1PGK2MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0506772-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1992-10-07 EP claimed
WO-1991009604-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1991-07-11 WO claimed
US-9994876-B2 Engineering microbes and metabolic pathways for the production of ethylene glycol MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-06-12 US disclosed
US-20160076061-A1 ENGINEERING MICROBES AND METABOLIC PATHWAYS FOR THE PRODUCTION OF ETHYLENE GLYCOL MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-03-17 US disclosed
US-20130316416-A1 ENGINEERING MICROBES AND METABOLIC PATHWAYS FOR THE PRODUCTION OF ETHYLENE GLYCOL MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-11-28 US disclosed
WO-2013126721-A1 ENGINEERING MICROBES AND METABOLIC PATHWAYS FOR THE PRODUCTION OF ETHYLENE GLYCOL MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-08-29 WO disclosed