Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670515 | 0.82 | LTB4R2 (0.44) | LTB4R2CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL4632782 | 0.81 | MEN1 (0.44) | LTB4R2CYP1A2CYP3A4CYP2C19CETP | |
| SCHEMBL4499074 | 0.81 | LTB4R2 (0.45) | LTB4R2CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL440958 | 0.77 | RXFP1 (0.43) | LTB4R2CYP1A2CYP3A4CYP2C19CETP | |
| SCHEMBL5802953 | 0.76 | RXFP1 (0.42) | LTB4R2CYP1A2CYP3A4CYP2C19HDAC1 | |
| SCHEMBL29042373 | 0.76 | RXFP1 (0.42) | LTB4R2CYP1A2CYP3A4CYP2C19HDAC1 | |
| SCHEMBL12707645 | 0.76 | HDAC8 (0.56) | LTB4R2CYP1A2CYP3A4CYP2C19HDAC1 | |
| SCHEMBL1007873 | 0.76 | RXFP1 (0.42) | LTB4R2CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9135626 | 0.75 | CYP1A2 (0.43) | LTB4R2CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL19745812 | 0.74 | HDAC1 (0.49) | LTB4R2MEN1KMT2AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110947-A | Process for the preparation of 3-carboalkoxypyrrolidones | ICI AMERICAS INC. (US) | 1992-05-05 | — | — | US | disclosed |
| WO-1990007499-A1 | PROCESS FOR THE PREPARATION OF 3-CARBOALKOXYPYRROLIDONES | ICI AMERICAS INC. (US) | 1990-07-12 | — | — | WO | disclosed |
| WO-1990007497-A1 | PROCESS FOR THE PREPARATION OF 3-ACYLPYRROLIDONES | ICI AMERICAS INC. (US) | 1990-07-12 | — | — | WO | disclosed |
| US-4874873-A | Process for the preparation of 3-acylpyrrolidones | ICI AMERICAS INC. (US) | 1989-10-17 | — | — | US | disclosed |
| US-4724261-A | CHEMICAL INTERMEDIATE FOR ANILINO ALKANONE HERBICIDES | STAUFFER CHEMICAL COMPANY (US) | 1988-02-09 | — | — | US | disclosed |