Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1254752 | 0.82 | KDM4E (0.41) | ABCB1MTNR1AMTNR1BKDM4EHPGD | |
| SCHEMBL4670589 | 0.79 | PTPN1 (0.47) | RAB9ACYP3A4SMN1; SMN2HTTLMNA | |
| SCHEMBL718444 | 0.78 | ABCB1 (0.44) | ABCB1NQO1KDM4EHPGDHSD17B10 | |
| SCHEMBL4670194 | 0.74 | MCL1 (0.68) | PPARGABCB1NQO1MTNR1AMTNR1B | |
| SCHEMBL4143926 | 0.74 | ALDH1A1 (0.40) | ABCB1NQO1RAB9AKDM4EHPGD | |
| SCHEMBL30956080 | 0.74 | ALDH1A1 (0.37) | ABCB1NQO1RAB9AKDM4EHPGD | |
| SCHEMBL4672785 | 0.72 | MCL1 (0.53) | PPARGABCB1NQO1MTNR1AMTNR1B | |
| SCHEMBL29502989 | 0.72 | NPC1 (0.44) | NQO1MTNR1ARAB9AKDM4EHPGD | |
| SCHEMBL18702818 | 0.72 | NPC1 (0.44) | NQO1MTNR1ARAB9AKDM4EHPGD | |
| SCHEMBL16540650 | 0.71 | MAPT (0.57) | RAB9AKDM4EHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017464-A1 | PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 | NOE CHRISTIAN R (AT) | 1992-10-15 | — | — | WO | disclosed |