SCHEMBL9738420

SCHEMBL9738420

CNc1nc(Cl)nc2c1ncn2Cc1ccccc1Cl

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738136 0.89 YTHDC1 (0.63) YTHDC1
SCHEMBL27388375 0.88 YTHDC1 (1.00) YTHDC1
SCHEMBL9739440 0.88 YTHDC1 (0.75) YTHDC1
SCHEMBL9739343 0.88 YTHDC1 (0.68) YTHDC1
SCHEMBL27388307 0.86 YTHDC1 (1.00) YTHDC1
SCHEMBL9738081 0.86 YTHDC1 (0.59) YTHDC1
SCHEMBL27388300 0.86 YTHDC1 (1.00) YTHDC1
SCHEMBL27388392 0.85 YTHDC1 (1.00) YTHDC1
SCHEMBL27387508 0.83 YTHDC1 (1.00) YTHDC1
SCHEMBL22345218 0.83 YTHDC1 (0.54) YTHDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363320-A2 Substituted 9H purine CIBA-GEIGY AG (CH) 1990-04-11 EP claimed
US-5110818-A Antiepileptic agents CIBA-GEIGY CORPORATION (US) 1992-05-05 US disclosed
EP-0363320-A2 Substituted 9H purine CIBA-GEIGY AG (CH) 1990-04-11 EP disclosed