SCHEMBL9738422

SCHEMBL9738422

O=C(COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H](O)CO

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGD P52209 3/20 0.43
PDE4A P27815 1/20 0.39
TPI1 P60174 1/20 0.38
LMNA P02545 2/20 0.37
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
MPI P34949 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16322088 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL4136973 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL4131096 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL19512307 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL9737043 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL8472515 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL851610 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
SCHEMBL24438 1.00 PGD (0.43) PGDPDE4ATPI1LMNAPGK1
Phosphoric Acid SCHEMBL18011882 0.98 PGD (0.42) PGDPDE4ATPI1LMNAPGK1
SCHEMBL8142384 0.98 PGD (0.42) PGDPDE4ATPI1LMNAPGK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015011222-A1 ACTIVATION OF RAS BY A FRUCTOSE-1,6-BISPHOSPHATE / GUANINE NUCLEOTIDE EXCHANGE PROTEIN COMPLEX VIB VZW (BE) 2015-01-29 WO claimed
EP-0506772-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1992-10-07 EP claimed
WO-1991009604-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1991-07-11 WO claimed
WO-2015011222-A1 ACTIVATION OF RAS BY A FRUCTOSE-1,6-BISPHOSPHATE / GUANINE NUCLEOTIDE EXCHANGE PROTEIN COMPLEX VIB VZW (BE) 2015-01-29 WO disclosed
EP-0506772-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1992-10-07 EP disclosed
WO-1991009604-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A PHOSPHOSUGAR PERSTORP AB (SE) 1991-07-11 WO disclosed