Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740021 | 1.00 | KEAP1 (0.68) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL16173592 | 1.00 | KEAP1 (0.68) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11609926 | 1.00 | KEAP1 (0.68) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL7103406 | 1.00 | KEAP1 (0.68) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL7239607 | 0.97 | KEAP1 (0.71) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL1998867 | 0.91 | KEAP1 (0.71) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL22048302 | 0.90 | HRH3 (0.71) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL17377315 | 0.89 | KEAP1 (0.62) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| Ammonia Solution, Strong SCHEMBL9400430 | 0.88 | KEAP1 (0.68) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11222517 | 0.88 | KEAP1 (0.68) | KEAP1SMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120731-A | For use as oxygen carriers in blood substitutes | KALIE-CHEMIE AG (DE) | 1992-06-09 | — | — | US | disclosed |