Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9205890 | 0.89 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL9201664 | 0.85 | SIGMAR1 (0.64) | SIGMAR1 | |
| Oxalic Acid SCHEMBL9205537 | 0.85 | SIGMAR1 (0.66) | SIGMAR1 | |
| Oxalic Acid SCHEMBL9202249 | 0.83 | BCHE (0.60) | SIGMAR1 | |
| SCHEMBL9204614 | 0.81 | SIGMAR1 (0.68) | SIGMAR1 | |
| SCHEMBL9206183 | 0.79 | BCHE (0.61) | SIGMAR1 | |
| Oxalic Acid SCHEMBL9203704 | 0.79 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL8786638 | 0.73 | SIGMAR1 (0.85) | SIGMAR1 | |
| SCHEMBL8786840 | 0.72 | SIGMAR1 (0.83) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8787075 | 0.72 | SIGMAR1 (0.82) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114941-A | PYRIMIDINEDIONE DERIVATIVE COMPOUNDS, METHOD FOR PREPARING SAME, AND ANTIARRYTHMIC AGENTS CONTAINING SAME | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-19 | — | — | US | disclosed |