SCHEMBL9738706

SCHEMBL9738706

CCCCCCCNC(=O)Oc1ccc2c(ccn2NC(CC)c2ccncc2F)c1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
PTGS2 P35354 6/20 0.41
FAAH O00519 4/20 0.41
MGLL Q99685 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9671926 0.99 BCHE (0.46) BCHEPTGS2FAAHMGLL
SCHEMBL9738851 0.97 BCHE (0.50) BCHEPTGS2FAAHMGLL
Hydrochloric Acid SCHEMBL9671998 0.96 BCHE (0.49) BCHEPTGS2FAAHMGLL
SCHEMBL8539328 0.87 BCHE (0.51) BCHE
SCHEMBL8537927 0.86 BCHE (0.58) BCHEPTGS2FAAH
SCHEMBL8543797 0.83 BCHE (0.62) BCHEFAAH
SCHEMBL9738702 0.83 BCHE (0.48) BCHEMGLL
Hydrochloric Acid SCHEMBL9671922 0.82 BCHE (0.47) BCHEMGLL
SCHEMBL9738844 0.79 BCHE (0.51) BCHEFAAHMGLL
Hydrochloric Acid SCHEMBL9671993 0.78 BCHE (0.50) BCHEFAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5102891-A Useful for treating various memory dysfunctions such as alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1992-04-07 US claimed
US-5102891-A Useful for treating various memory dysfunctions such as alzheimer's disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1992-04-07 US disclosed