Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537927 | 0.97 | BCHE (0.58) | BCHEACHEFAAH | |
| SCHEMBL8539761 | 0.89 | ACHE (0.70) | BCHEACHEALDH1A1 | |
| SCHEMBL8543197 | 0.87 | BCHE (0.62) | BCHEACHEFAAH | |
| SCHEMBL9738851 | 0.86 | BCHE (0.50) | BCHEACHEFAAHLIPE | |
| Hydrochloric Acid SCHEMBL9671998 | 0.85 | BCHE (0.49) | BCHEACHEFAAHLIPE | |
| SCHEMBL9738706 | 0.83 | BCHE (0.47) | BCHEFAAH | |
| Hydrochloric Acid SCHEMBL9671926 | 0.82 | BCHE (0.46) | BCHEFAAH | |
| SCHEMBL8543795 | 0.82 | BCHE (0.64) | BCHEACHEFAAHLIPE | |
| SCHEMBL9672315 | 0.80 | BCHE (0.49) | BCHEACHELIPE | |
| SCHEMBL8537924 | 0.79 | BCHE (0.60) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | claimed |
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| US-5102891-A | Useful for treating various memory dysfunctions such as alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-04-07 | — | — | US | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |