Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9741653 | 0.99 | KDM4E (0.45) | KDM4EL3MBTL1HRH3ALDH1A1MAPT | |
| SCHEMBL9739297 | 0.92 | HRH3 (0.48) | KDM4EHRH3ALDH1A1TSHRHRH1 | |
| Hydrochloric Acid SCHEMBL9213581 | 0.91 | KDM4E (0.46) | KDM4EL3MBTL1HRH3ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9739482 | 0.89 | HRH3 (0.44) | HRH3MAPTTSHRHRH1DRD2 | |
| Hydrochloric Acid SCHEMBL9215867 | 0.88 | KDM4E (0.47) | KDM4EL3MBTL1HRH3HRH1DRD2 | |
| SCHEMBL10722947 | 0.87 | HRH3 (0.39) | KDM4EHRH3ALDH1A1HRH1DRD2 | |
| SCHEMBL9739972 | 0.87 | LMNA (0.46) | KDM4EHRH3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9738996 | 0.86 | HRH3 (0.48) | HRH3MAPTTSHRHRH1DRD2 | |
| Hydrochloric Acid SCHEMBL9740921 | 0.86 | LMNA (0.45) | KDM4EHRH3ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9740789 | 0.86 | KDM4E (0.48) | KDM4EL3MBTL1HRH3ALDH1A1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0224794-B1 | CYCLIC AMINE DERIVATIVES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |