Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 1.00 |
| ▸ | TOP2A | P11388 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9740283 | 0.99 | ABCB1 (0.97) | ABCB1TOP2AKDM4EGAALMNA | |
| SCHEMBL9739975 | 0.86 | ABCB1 (1.00) | ABCB1TOP2AGAALMNAL3MBTL1 | |
| SCHEMBL9738669 | 0.86 | ABCB1 (1.00) | ABCB1TOP2AGAALMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9741907 | 0.85 | ABCB1 (0.98) | ABCB1TOP2AGAALMNAL3MBTL1 | |
| SCHEMBL9739038 | 0.85 | ABCB1 (0.74) | ABCB1TOP2AKDM4EGAALMNA | |
| Hydrochloric Acid SCHEMBL9738650 | 0.84 | ABCB1 (0.72) | ABCB1TOP2AKDM4EGAALMNA | |
| SCHEMBL9739041 | 0.79 | ABCB1 (0.65) | ABCB1TOP2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL9746106 | 0.78 | ABCB1 (0.64) | ABCB1TOP2AKDM4ELMNAL3MBTL1 | |
| SCHEMBL721278 | 0.77 | ABCB1 (0.63) | ABCB1KDM4ELMNAL3MBTL1TP53 | |
| SCHEMBL13320401 | 0.73 | ABCB1 (0.56) | ABCB1KDM4ELMNAL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017464-A1 | PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 | NOE CHRISTIAN R (AT) | 1992-10-15 | — | — | WO | claimed |
| WO-1992017464-A1 | PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 | NOE CHRISTIAN R (AT) | 1992-10-15 | — | — | WO | disclosed |