Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.64 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739983 | 0.85 | ABCB1 (0.67) | ABCB1ADRB2LMNAHIF1AKCNH2 | |
| SCHEMBL9739041 | 0.84 | ABCB1 (0.65) | ABCB1TOP2AADRB2LMNAHIF1A | |
| SCHEMBL9739016 | 0.78 | ABCB1 (1.00) | ABCB1TOP2ALMNAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9740283 | 0.77 | ABCB1 (0.97) | ABCB1TOP2AADRB2LMNAKDM4E | |
| SCHEMBL9739038 | 0.76 | ABCB1 (0.74) | ABCB1TOP2ALMNAKCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL9738650 | 0.75 | ABCB1 (0.72) | ABCB1TOP2ALMNAKCNH2KDM4E | |
| SCHEMBL9738669 | 0.70 | ABCB1 (1.00) | ABCB1TOP2AADRB2LMNAHIF1A | |
| SCHEMBL9739975 | 0.70 | ABCB1 (1.00) | ABCB1TOP2AADRB2LMNAHIF1A | |
| SCHEMBL9677979 | 0.70 | KDM4E (0.70) | ABCB1ADRB2LMNAKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9741907 | 0.70 | ABCB1 (0.98) | ABCB1TOP2AADRB2LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017464-A1 | PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 | NOE CHRISTIAN R (AT) | 1992-10-15 | — | — | WO | disclosed |