Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098891 | 0.94 | GAA (0.55) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL9126935 | 0.87 | GAA (0.56) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL9127057 | 0.86 | TSHR (0.50) | GAATSHRSMN1; SMN2CDK1MAPT | |
| SCHEMBL10642716 | 0.86 | GAA (0.50) | GAATSHRSMN1; SMN2CDK1MAPT | |
| SCHEMBL7452294 | 0.86 | GAA (0.47) | GAATSHRSMN1; SMN2CDK1MAPT | |
| SCHEMBL9127660 | 0.84 | GAA (0.53) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL11130838 | 0.84 | GAA (0.57) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL7806542 | 0.83 | GAA (0.53) | GAACDK1MAPTKDM4ENPC1 | |
| SCHEMBL10569768 | 0.83 | GAA (0.51) | GAATSHRSMN1; SMN2CDK1MAPT | |
| SCHEMBL27535143 | 0.83 | GAA (0.40) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992015568-A1 | BENZENESULFONYLUREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-17 | — | — | WO | claimed |