Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739203 | 1.00 | KMT2A (0.47) | KMT2AMEN1ATMMAPTCTDSP1 | |
| SCHEMBL9734396 | 0.80 | CES1 (0.56) | KMT2AMEN1MAPTNPSR1NR1H2 | |
| SCHEMBL29168855 | 0.77 | KMT2A (0.62) | KMT2AMEN1NR1H2NR1H3KDM5A | |
| SCHEMBL30758617 | 0.77 | KMT2A (0.62) | KMT2AMEN1NR1H2NR1H3KDM5A | |
| SCHEMBL6322884 | 0.76 | ALDH1A1 (0.61) | KMT2AMEN1MAPTCTDSP1NPSR1 | |
| SCHEMBL6322887 | 0.76 | ALDH1A1 (0.61) | KMT2AMEN1MAPTCTDSP1NPSR1 | |
| SCHEMBL13628014 | 0.76 | ALDH1A1 (0.61) | KMT2AMEN1MAPTCTDSP1NPSR1 | |
| SCHEMBL9734125 | 0.74 | BCL2A1 (0.40) | KMT2AMEN1ATMMAPTCTDSP1 | |
| SCHEMBL9734120 | 0.74 | BCL2A1 (0.40) | KMT2AMEN1ATMMAPTCTDSP1 | |
| SCHEMBL5194875 | 0.73 | TTR (0.65) | KMT2AMEN1ATMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155110-A | Antiinflammatory agents, analgesics, antipyretics | WARNER-LAMBERT COMPANY (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0316630-A1 | Novel fenamic acid hydroxamate derivatives having cyclooxygenase and 5-lipoxygenase inhibition | WARNER-LAMBERT COMPANY (US) | 1989-05-24 | — | — | EP | disclosed |
| WO-1989003818-A1 | NOVEL FENAMIC ACID HYDROXAMATE DERIVATIVES HAVING CYCLOOXYGENASE AND 5-LIPOXYGENASE INHIBITION | WARNER-LAMBERT COMPANY (US) | 1989-05-05 | — | — | WO | disclosed |