Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957572 | 0.92 | MAPT (0.58) | KMT2AMAPTKDM4EMAPK1LMNA | |
| SCHEMBL3708228 | 0.85 | TAAR1 (0.61) | KMT2AMAPTKDM4EMAPK1LMNA | |
| SCHEMBL14368046 | 0.82 | NPC1 (0.54) | KMT2AMAPTKDM4EMAPK1LMNA | |
| SCHEMBL3718787 | 0.81 | NPC1 (0.53) | KMT2AMAPTKDM4EMAPK1LMNA | |
| SCHEMBL4544826 | 0.80 | NFKB1 (0.73) | KMT2AMAPTKDM4EMAPK1LMNA | |
| SCHEMBL4544792 | 0.80 | NFKB1 (0.73) | KMT2AMAPTKDM4EMAPK1LMNA | |
| SCHEMBL18037971 | 0.80 | KMT2A (1.00) | KMT2AMAPTLMNASMN1; SMN2NFKB1 | |
| SCHEMBL4544831 | 0.79 | APP (0.62) | KMT2AMAPTKDM4EMAPK1NFKB1 | |
| SCHEMBL11291398 | 0.78 | SYK (0.59) | KMT2AMAPTKDM4EMAPK1ABCB1 | |
| SCHEMBL8526184 | 0.78 | NFKB1 (0.69) | KMT2AMAPTKDM4EMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337943-A2 | N-Phenyl-N-pyrimidin-2-yl-ureas with herbicidal and plant-growth regulating activity | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | claimed |
| US-5159078-A | Herbicides, plant growth regulator | CIBA-GEIGY CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-4966622-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1990-10-30 | — | — | US | disclosed |
| EP-0337943-A2 | N-Phenyl-N-pyrimidin-2-yl-ureas with herbicidal and plant-growth regulating activity | CIBA-GEIGY AG (CH) | 1989-10-18 | — | — | EP | disclosed |