Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739129 | 0.90 | AGTR1 (0.35) | AGTR1AGTR2CNR2 | |
| SCHEMBL9738526 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9738817 | 0.89 | CNR2 (0.34) | AGTR1AGTR2CNR2 | |
| SCHEMBL9738101 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9740212 | 0.85 | AGTR1 (0.35) | AGTR1AGTR2CNR2 | |
| SCHEMBL9737759 | 0.85 | TRPV1 (0.33) | AGTR1AGTR2 | |
| SCHEMBL9739085 | 0.85 | AGTR1 (0.36) | AGTR1AGTR2CNR2 | |
| SCHEMBL9739175 | 0.85 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9738552 | 0.83 | SLC33A1 (0.34) | AGTR1 | |
| SCHEMBL9552979 | 0.81 | AGTR1 (0.39) | AGTR1AGTR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | claimed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |