Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9740113 | 0.99 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1GAADRD1DRD4 | |
| SCHEMBL9740167 | 0.99 | MTNR1B (0.43) | SMN1; SMN2ALDH1A1GAADRD1DRD4 | |
| SCHEMBL9740418 | 0.92 | ABCB1 (0.46) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9739319 | 0.92 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1GAADRD1DRD4 | |
| SCHEMBL10375616 | 0.91 | HRH3 (0.43) | SMN1; SMN2ALDH1A1GAADRD1DRD4 | |
| SCHEMBL9739107 | 0.91 | HRH3 (0.48) | SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL9739564 | 0.91 | CYP3A4 (0.41) | SMN1; SMN2ALDH1A1GAADRD1DRD4 | |
| SCHEMBL9739180 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1GAADRD1DRD4 | |
| Hydrochloric Acid SCHEMBL9740153 | 0.91 | ABCB1 (0.45) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9740219 | 0.91 | HCN4 (0.49) | SMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0224794-B1 | CYCLIC AMINE DERIVATIVES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |