Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21950819 | 0.95 | LMNA (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL3674153 | 0.95 | LMNA (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL19832371 | 0.70 | LMNA (0.42) | LMNACA12CA1CA2CA3 | |
| SCHEMBL20192427 | 0.70 | CHRM2 (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL29256397 | 0.69 | LMNA (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL25135264 | 0.68 | CHRM2 (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL19075208 | 0.68 | CHRM2 (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL10581989 | 0.68 | — | — | |
| SCHEMBL21606387 | 0.67 | CHRM2 (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL18612367 | 0.67 | CHRM2 (0.45) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5159079-A | 2-piperidones as intermediates for 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids | ELI LILLY AND COMPANY (US) | 1992-10-27 | — | — | US | disclosed |