Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849454 | 1.00 | REN (0.53) | REN | |
| SCHEMBL9849486 | 0.89 | REN (0.58) | REN | |
| SCHEMBL9849491 | 0.89 | REN (0.58) | REN | |
| SCHEMBL6013387 | 0.89 | REN (0.57) | REN | |
| SCHEMBL7382620 | 0.89 | REN (0.56) | REN | |
| SCHEMBL9740429 | 0.89 | REN (0.55) | REN | |
| SCHEMBL9740426 | 0.89 | REN (0.55) | REN | |
| SCHEMBL7327140 | 0.87 | REN (0.58) | REN | |
| SCHEMBL10421591 | 0.87 | REN (0.56) | REN | |
| SCHEMBL9742947 | 0.87 | REN (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |