Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.81 |
| ▸ | FBP1 | P09467 | 5/20 | 0.56 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432682 | 0.85 | GRIN1 (0.71) | GRIN1FBP1GPR17 | |
| SCHEMBL9433912 | 0.84 | GRIN1 (0.68) | GRIN1FBP1GPR17 | |
| SCHEMBL9731831 | 0.83 | GRIN1 (0.80) | GRIN1FBP1GPR17 | |
| SCHEMBL9731514 | 0.83 | GRIN1 (0.68) | GRIN1FBP1GPR17 | |
| SCHEMBL9731281 | 0.80 | GRIN1 (0.67) | GRIN1FBP1GPR17 | |
| SCHEMBL9732614 | 0.80 | GRIN1 (0.69) | GRIN1FBP1GPR17 | |
| SCHEMBL9732016 | 0.79 | GRIN1 (0.60) | GRIN1FBP1GPR17 | |
| SCHEMBL9739526 | 0.77 | GRIN1 (0.77) | GRIN1FBP1GPR17 | |
| SCHEMBL4342185 | 0.74 | GRIN1 (0.66) | GRIN1GPR17 | |
| SCHEMBL9709075 | 0.74 | GPR17 (0.71) | GRIN1GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020649-A2 | SUBSTITUTED 2-CARBOXYINDOLES HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-11-26 | — | — | WO | claimed |
| WO-1992020649-A2 | SUBSTITUTED 2-CARBOXYINDOLES HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |