Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636048 | 1.00 | PARP15 (0.55) | PARP15PARP10SRD5A2FAAHEPHX2 | |
| SCHEMBL8921736 | 0.92 | PARP15 (0.50) | PARP15PARP10SRD5A2FAAHEPHX2 | |
| SCHEMBL8923504 | 0.90 | PARP15 (0.51) | PARP15PARP10SRD5A2FAAHEPHX2 | |
| SCHEMBL336470 | 0.89 | SRD5A2 (0.61) | SRD5A2EPHX2TSHRALDH1A1CA1 | |
| SCHEMBL16429183 | 0.88 | AKR1C3 (0.62) | PARP15PARP10SRD5A2ALDH1A1MAPK14 | |
| SCHEMBL9742817 | 0.87 | SRD5A2 (0.68) | PARP15PARP10SRD5A2ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19837805 | 0.87 | SRD5A2 (0.59) | SRD5A2EPHX2TSHRALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL8505603 | 0.87 | SRD5A2 (0.59) | SRD5A2EPHX2TSHRALDH1A1CA1 | |
| SCHEMBL21656834 | 0.86 | PARP15 (0.55) | PARP15PARP10SRD5A2FAAHEPHX2 | |
| SCHEMBL21656465 | 0.86 | PARP15 (0.55) | PARP15PARP10SRD5A2FAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110983-A | Intermediates for heat-resistant polyamides and polyimides | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-05 | — | — | US | disclosed |
| EP-0389961-A1 | Monomerides containing the hexafluoroisopropyl group, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-03 | — | — | EP | disclosed |