Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 5/20 | 0.64 |
| ▸ | MGAM | O43451 | 1/20 | 0.64 |
| ▸ | SI | P14410 | 1/20 | 0.64 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 5/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155563 | 0.85 | GAA (0.78) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL28650988 | 0.82 | GAA (0.74) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL4639848 | 0.82 | FAAH (0.72) | ALDH1A1TRPA1GAAMGAMSI | |
| Malonic Acid Diethyl Ester SCHEMBL28123398 | 0.81 | GAA (0.71) | ALDH1A1TRPA1GAAMGAMSI | |
| Malonic Acid Diethyl Ester SCHEMBL8677179 | 0.80 | GAA (0.79) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL181997 | 0.80 | GAA (0.70) | ALDH1A1TRPA1GAAMGAMSI | |
| Ethyl Bromo Acetate SCHEMBL1332372 | 0.79 | — | — | |
| Ethyl Bromo Acetate SCHEMBL1332675 | 0.79 | — | — | |
| Ethyl Bromo Acetate SCHEMBL1332025 | 0.79 | — | — | |
| Ethyl Bromo Acetate SCHEMBL5658 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466915-A | Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-116370632-A | Cold gel for preventing chapped skin by combining photodynamic therapy and preparation method thereof | 杭州惠康医疗器械有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-113336703-B | Synthesis of 1,3,4, 5-tetrasubstituted 1H-pyrazole derivatives | 西华大学 | 2023-05-12 | — | — | CN | claimed |
| CN-115772137-A | Preparation method of febuxostat | 济宁晟泰药业有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-112374994-B | Preparation method of pentafluoroaniline | 衢州学院 | 2022-07-01 | — | — | CN | claimed |
| CN-111995584-B | Preparation method of oxalagrill intermediate | 常州工学院 | 2022-03-29 | — | — | CN | claimed |
| CN-109053479-B | Method for synthesizing quaternary amine inner salt | 兆科药业（合肥）有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-112374994-A | Preparation method of pentafluoroaniline | 衢州学院 | 2021-02-19 | — | — | CN | claimed |
| CN-111995584-A | Preparation method of oxalagrill intermediate | 常州工学院 | 2020-11-27 | — | — | CN | claimed |
| CN-108169399-B | Method for separating impurities in ethyl demethylaminothiazolyloximate crude product | 山东金城医药化工有限公司 | 2020-10-09 | — | — | CN | claimed |
| EP-0967271-B1 | NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE | KANEKA CORP (JP) | 2004-10-20 | — | — | EP | claimed |
| EP-1416050-A1 | METHOD OF MODIFYING ENZYME AND OXIDOREDUCTASE VARIANT | KANEKA CORPORATION (JP) | 2004-05-06 | — | — | EP | claimed |
| US-20040082043-A1 | Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root daucus carota | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-04-29 | — | — | US | claimed |
| US-6448052-B2 | TO CONVERT ETHYL 4-CHLOROACETOACETATE USING NADPH AS A COENZYME TO PRODUCE ETHYL (S)-4-CHLORO-3-HYDROXYBUTYRATE; SUBSTRATE SPECIFICITY, NO ACTIVITY TO ETHYL ACETOACETATE, SPECIFIED OPTIMAL PH AND TEMPERATURE; ENZYME FROM CANDIDA | KANEKA CORPORATION (JP) | 2002-09-10 | — | — | US | claimed |
| EP-0902016-B1 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2002-05-02 | — | — | EP | claimed |
| US-20020006651-A1 | Carbonyl reductase enzyme and methods for its use | KANEKA CORPORATION | 2002-01-17 | — | — | US | claimed |
| US-6046337-A | Process for the preparation of a dihydropyridine derivative | EGIS GYOGYSZERGYAR RT. (HU) | 2000-04-04 | — | — | US | claimed |
| EP-0967271-A1 | NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE | KANEKA CORPORATION (JP) | 1999-12-29 | — | — | EP | claimed |
| EP-0902016-A1 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGIS GYOGYSZERGYAR (HU) | 1999-03-17 | — | — | EP | claimed |
| EP-0902016-A2 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGIS GYOGYSZERGYAR RT. (HU) | 1999-03-17 | — | — | EP | claimed |