Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.56 |
| ▸ | PPARG | P37231 | 16/20 | 0.56 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739383 | 0.91 | PPARA (0.61) | PPARAPPARG | |
| SCHEMBL4013883 | 0.73 | PPARA (0.82) | PPARAPPARG | |
| SCHEMBL4012619 | 0.72 | PPARA (0.84) | PPARAPPARG | |
| SCHEMBL13924214 | 0.72 | PPARA (0.84) | PPARAPPARG | |
| SCHEMBL9126457 | 0.72 | PPARA (0.54) | PPARAPPARGGCGR | |
| SCHEMBL4011903 | 0.71 | PPARG (0.51) | PPARAPPARG | |
| SCHEMBL9128765 | 0.71 | PPARA (0.53) | PPARAPPARGGCGR | |
| SCHEMBL9739158 | 0.71 | PRKCI (0.42) | PPARAPPARGPRKCI | |
| SCHEMBL9739521 | 0.70 | PRKCI (0.56) | PRKCI | |
| SCHEMBL9307429 | 0.70 | PPARA (0.53) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087638-A | Inhibitors of mammalian leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1992-02-11 | — | — | US | disclosed |
| EP-0338782-A1 | Benzofuran derivatives | MERCK FROSST CANADA INC. (CA) | 1989-10-25 | — | — | EP | disclosed |
| US-4863958-A | TREATING ALLERGIC CONDITIONS, ASTHMA, CARDIOVASCULAR DISORDERS, AND INFLAMMATION | MERCK FROSST CANADA, INC. (CA) | 1989-09-05 | — | — | US | disclosed |