Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207738 | 0.74 | AHR (0.42) | — | |
| SCHEMBL5365900 | 0.71 | TAAR1 (0.49) | — | |
| SCHEMBL1399575 | 0.70 | NOS1 (0.35) | — | |
| SCHEMBL2971945 | 0.70 | KDM4E (0.35) | — | |
| SCHEMBL4851597 | 0.69 | — | — | |
| SCHEMBL9739044 | 0.68 | APEX1 (0.44) | APEX1 | |
| SCHEMBL207776 | 0.66 | AHR (0.42) | — | |
| SCHEMBL207490 | 0.66 | AHR (0.42) | — | |
| SCHEMBL208360 | 0.66 | CA12 (0.38) | — | |
| SCHEMBL7170676 | 0.64 | APEX1 (1.00) | APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |