Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014473 | 0.84 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL221092 | 0.83 | ALDH1A1 (0.72) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL8610167 | 0.81 | ALDH1A1 (0.65) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL4279628 | 0.81 | ALDH1A1 (0.65) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL28658136 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL1562501 | 0.79 | ALDH1A1 (0.61) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL2177071 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL17650674 | 0.78 | GAA (0.64) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL13545621 | 0.78 | GAA (0.69) | ALDH1A1CYP1A2CYP2C9GAAMEN1 | |
| SCHEMBL4267439 | 0.77 | ALDH1A1 (0.59) | ALDH1A1CYP1A2CYP2C9GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112968-A | Monobactam hydrazide derivatives | E. R. SQUIBB & SONS, INC. (US) | 1992-05-12 | — | — | US | disclosed |