Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11831020 | 0.81 | TSHR (0.56) | TDP1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4303054 | 0.79 | TDP1 (0.42) | TDP1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28215127 | 0.75 | TDP1 (0.56) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL4308681 | 0.75 | SMN1; SMN2 (0.40) | KDM4EPOLBALDH1A1MAPTCYP1A2 | |
| SCHEMBL9739241 | 0.75 | MAPT (0.36) | L3MBTL1KDM4EPOLBMEN1KMT2A | |
| SCHEMBL1554959 | 0.75 | TDP1 (0.52) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL29625716 | 0.73 | NCEH1 (0.64) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL4594864 | 0.73 | NCEH1 (0.64) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL8904048 | 0.73 | NSD2 (0.36) | KDM4EKMT2AALDH1A1NCEH1MAPT | |
| SCHEMBL1179747 | 0.73 | TDP1 (0.62) | TDP1L3MBTL1KDM4EPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |