Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9739412 | 0.99 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL9741218 | 0.94 | MEN1 (0.40) | MEN1KMT2ANPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL10376910 | 0.94 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL9739546 | 0.90 | HCN4 (0.49) | MEN1KMT2AGAAMCHR1ABCB1 | |
| SCHEMBL9739498 | 0.90 | ABCB1 (0.51) | MEN1KMT2ANPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL9738957 | 0.89 | CYP3A4 (0.50) | MEN1KMT2AGAAMCHR1ABCB1 | |
| Hydrochloric Acid SCHEMBL9215351 | 0.89 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL9739563 | 0.89 | GAA (0.51) | MEN1KMT2ANPC1RAB9AGAA | |
| SCHEMBL9739483 | 0.89 | LTA4H (0.42) | MEN1KMT2AMCHR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9740652 | 0.88 | LTA4H (0.42) | MEN1KMT2AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0224794-B1 | CYCLIC AMINE DERIVATIVES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |