Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | MERTK | Q12866 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738116 | 0.87 | ADORA2A (0.60) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL9738800 | 0.86 | PDE4A (0.50) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL9738982 | 0.85 | PDE4A (0.52) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL25547346 | 0.84 | ADORA2A (0.63) | ADORA2AADORA1AXLMERTKFLT3 | |
| SCHEMBL9738497 | 0.83 | AXL (0.51) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL9738975 | 0.83 | ADORA2A (0.65) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL9738619 | 0.81 | PDE4A (0.46) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL23416524 | 0.81 | ADORA2A (0.63) | ADORA2AADORA1 | |
| SCHEMBL10442061 | 0.81 | CYP1A2 (0.61) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9739172 | 0.81 | ADORA2A (0.51) | ADORA2AADORA1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110818-A | Antiepileptic agents | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |