Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 13/20 | 0.67 |
| ▸ | HBB | P68871 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | EDNRA | P25101 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.65 |
| ▸ | POLG | P54098 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | VCP | P55072 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7919757 | 0.87 | PNP (0.57) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL9662638 | 0.85 | BLM (0.55) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL10564406 | 0.85 | BLM (0.55) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL10400436 | 0.85 | BLM (0.55) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL28721440 | 0.84 | PNP (0.73) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL9741220 | 0.84 | PNP (0.84) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL29370760 | 0.83 | PNP (0.87) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL10558237 | 0.83 | PNP (0.60) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL10553712 | 0.83 | PNP (0.60) | PNPHBBBLMUSP2TSHR | |
| SCHEMBL8842615 | 0.83 | PNP (0.71) | PNPHBBBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098906-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4921859-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4918219-A | Glycerine derivatives | WARNER-LAMBERT COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4806642-A | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0145207-B1 | PURINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0145207-A1 | Purine derivatives | WARNER-LAMBERT COMPANY (US) | 1985-06-19 | — | — | EP | disclosed |