Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864363 | 0.84 | POLQ (0.58) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL187791 | 0.82 | POLQ (0.61) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL29718585 | 0.82 | POLQ (0.61) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL6971669 | 0.82 | POLQ (0.57) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL6714080 | 0.81 | POLQ (0.55) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL1395805 | 0.81 | POLQ (0.55) | POLQIDO1HDAC1HDAC8MAOB | |
| Hydrochloric Acid SCHEMBL2529825 | 0.81 | POLQ (0.59) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL265536 | 0.81 | POLQ (0.59) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL31173765 | 0.81 | POLQ (0.59) | POLQIDO1HDAC1HDAC8MAOB | |
| SCHEMBL643492 | 0.81 | POLQ (0.55) | POLQIDO1HDAC1HDAC8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |