Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173765 | 1.00 | POLQ (0.59) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL31402799 | 0.85 | POLQ (0.56) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL6864363 | 0.84 | POLQ (0.58) | POLQMAOBMAOAIDO1KDM4E | |
| Methyl Alcohol SCHEMBL8011354 | 0.83 | POLQ (0.62) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL6971669 | 0.82 | POLQ (0.57) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL29718585 | 0.82 | POLQ (0.61) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL8975793 | 0.82 | L3MBTL1 (0.46) | POLQMAOBMAOAKDM4EATM | |
| SCHEMBL187791 | 0.82 | POLQ (0.61) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL5238768 | 0.82 | POLQ (0.43) | POLQMAOBMAOAIDO1KDM4E | |
| SCHEMBL9911552 | 0.81 | POLQ (0.56) | POLQMAOBMAOAIDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840796-A | A kind of preparation method of trifluoromethyl alkene ester | 西安近代化学研究所 | 2018-03-27 | — | — | CN | claimed |
| CN-107619368-A | A kind of preparation method of trifluoromethyl alkene ether | 西安近代化学研究所 | 2018-01-23 | — | — | CN | claimed |
| EP-4293009-A2 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | Zogenix International Limited (GB) | 2023-12-20 | — | — | EP | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| US-20210147335-A1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| EP-3800177-A1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | Zogenix International Limited (GB) | 2021-04-07 | — | — | EP | disclosed |
| US-10947183-B2 | Fenfluramine compositions and methods of preparing the same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2021-03-16 | — | — | US | disclosed |
| EP-3393655-B1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LTD (GB) | 2020-12-09 | — | — | EP | disclosed |
| US-20190284124-A1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | ZOGENIX INTERNATIONAL LIMITED (GB) | 2019-09-19 | — | — | US | disclosed |
| US-10351510-B2 | Fenfluramine compositions and methods of preparing the same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2019-07-16 | — | — | US | disclosed |
| US-10351509-B2 | Fenfluramine compositions and methods of preparing the same | ZOGENIX INTERNATIONAL LIMITED (GB) | 2019-07-16 | — | — | US | disclosed |
| US-6376555-B1 | MUSCLE RELAXANTS | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-23 | — | — | US | disclosed |
| US-6346402-B1 | ACTS ON OPTICALLY ACTIVE (S)-ALPHA-PHENETHYLAMINE AND PYRUVIC ACID TO FORM ACETOPHENONE AND ALANINE; FOR PRODUCING CHEMICAL INTERMEDIATES OF DRUGS AND AGRICULTURAL CHEMICALS | KANEKA CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1135365-A1 | 4-3-SUBSTITUTED-AMINO-CYCLOBUT-3-ENE-1,2-DIONES AND USE FOR INFLUENCING SMOOTH MUSCLE CONTRACTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1045025-A1 | (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE | KANEKA CORPORATION (JP) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000034230-A1 | 4-3-SUBSTITUTED-AMINO-CYCLOBUT-3-ENE-1,2-DIONES AND USE FOR INFLUENCING SMOOTH MUSCLE CONTRACTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| US-5861532-A | Solid-phase synthesis of N-alkyl amides | CHIRON CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| EP-0198743-B1 | PROCESS FOR THE ELECTROSYNTHESIS OF KETONES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-05-31 | — | — | EP | disclosed |
| US-4629541-A | ELECTROCHEMICAL REDUCTION OF ORGANICS HALIDES IN THE PRESENCE OF ACID ANHYDRIDES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1986-12-16 | — | — | US | disclosed |
| EP-0198743-A1 | Process for the electrosynthesis of ketones | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147335-A1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | FAAH, FAAH2, TPH1 | POLQ 3426/4885MAOB 9/4885MAOA 7/4885 |
| US-10351510-B2 | Fenfluramine compositions and methods of preparing the same | FAAH, FAAH2, TPH1 | POLQ 3426/4885MAOB 9/4885MAOA 7/4885 |
| US-10351509-B2 | Fenfluramine compositions and methods of preparing the same | FAAH, FAAH2, TPH1 | POLQ 3426/4885MAOB 9/4885MAOA 7/4885 |
| US-20190284124-A1 | FENFLURAMINE COMPOSITIONS AND METHODS OF PREPARING THE SAME | FAAH, FAAH2, TPH1 | POLQ 3426/4885MAOB 9/4885MAOA 7/4885 |
| US-10947183-B2 | Fenfluramine compositions and methods of preparing the same | FAAH, FAAH2, TPH1 | POLQ 3426/4885MAOB 9/4885MAOA 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.